Comparative Analysis of Cell-Associated HIV DNA Levels in Cerebrospinal Fluid and Peripheral Blood by Droplet Digital PCR

BACKGROUND: Measurement of HIV DNA-bearing cells in cerebrospinal fluid (CSF) is challenging because few cells are present. We present a novel application of the sensitive droplet digital (dd)PCR in this context. METHODS: We analyzed CSF cell pellets and paired peripheral blood mononuclear cells (PB...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: de Oliveira, Michelli Faria, Gianella, Sara, Letendre, Scott, Scheffler, Konrad, Kosakovsky Pond, Sergei L., Smith, Davey M., Strain, Matt, Ellis, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592012/
https://ncbi.nlm.nih.gov/pubmed/26431315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139510
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