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An E2 Accessory Domain Increases Affinity for the Anaphase-promoting Complex and Ensures E2 Competition

The anaphase-promoting complex/cyclosome (APC/C) is a member of the RING family of E3 ubiquitin ligases, which promote ubiquitin transfer from an E2 ubiquitin-conjugating enzyme to a substrate. In budding yeast, the APC/C collaborates with two E2s, Ubc4 and Ubc1, to promote the initiation and elonga...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Girard, Juliet R., Tenthorey, Jeanette L., Morgan, David O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591839/
https://ncbi.nlm.nih.gov/pubmed/26306044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678193
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