The E3 Ubiquitin Ligases, HUWE1 and NEDD4-1, Are Involved in the Post-translational Regulation of the ABCG1 and ABCG4 Lipid Transporters

The ATP-binding cassette transporter ABCG1 has an essential role in cellular cholesterol homeostasis, and dysregulation has been associated with a number of high burden diseases. Previous studies reported that ABCG1 is ubiquitinated and degraded via the ubiquitin proteasome system. However, so far t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Aleidi, Shereen M., Howe, Vicky, Sharpe, Laura J., Yang, Alryel, Rao, Geetha, Brown, Andrew J., Gelissen, Ingrid C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Lipids
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591838/
https://ncbi.nlm.nih.gov/pubmed/26296893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675579
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