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Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition
Two large phosphatidylinositol 3-kinase–related protein kinases (PIKKs), ATM and ATR, play a central role in the DNA damage response pathway. PIKKs contain a highly conserved extreme C-terminus called the FRAP-ATM-TRRAP-C-terminal (FATC) domain. In budding yeast, ATM and ATR correspond to Tel1 and M...
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| Опубликовано в: : | Mol Biol Cell |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4591692/ https://ncbi.nlm.nih.gov/pubmed/26246601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0259 |
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