Loading...

Structural basis for stop codon recognition in eukaryotes

Termination of protein synthesis occurs when a translating ribosome encounters one of three universally conserved stop codons: UGA, UAA, or UAG. Release factors recognise stop codons in the ribosomal A site to mediate release of the nascent chain and recycling of the ribosome. Bacteria decode stop c...

Full description

Saved in:
Bibliographic Details
Published in:Nature
Main Authors: Brown, Alan, Shao, Sichen, Murray, Jason, Hegde, Ramanujan S., Ramakrishnan, V.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591471/
https://ncbi.nlm.nih.gov/pubmed/26245381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14896
Tags: Add Tag
No Tags, Be the first to tag this record!