Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor

All-trans retinoic acid (ATRA) is instrumental to male germ cell differentiation, but its mechanism of action remains elusive. To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB and RXRG) or all ATRA receptors (RARA, RARB a...

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Vydáno v:PLoS Genet
Hlavní autoři: Gely-Pernot, Aurore, Raverdeau, Mathilde, Teletin, Marius, Vernet, Nadège, Féret, Betty, Klopfenstein, Muriel, Dennefeld, Christine, Davidson, Irwin, Benoit, Gérard, Mark, Manuel, Ghyselinck, Norbert B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591280/
https://ncbi.nlm.nih.gov/pubmed/26427057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005501
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