Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor

All-trans retinoic acid (ATRA) is instrumental to male germ cell differentiation, but its mechanism of action remains elusive. To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB and RXRG) or all ATRA receptors (RARA, RARB a...

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Publicat a:PLoS Genet
Autors principals: Gely-Pernot, Aurore, Raverdeau, Mathilde, Teletin, Marius, Vernet, Nadège, Féret, Betty, Klopfenstein, Muriel, Dennefeld, Christine, Davidson, Irwin, Benoit, Gérard, Mark, Manuel, Ghyselinck, Norbert B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591280/
https://ncbi.nlm.nih.gov/pubmed/26427057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005501
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