Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor

All-trans retinoic acid (ATRA) is instrumental to male germ cell differentiation, but its mechanism of action remains elusive. To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB and RXRG) or all ATRA receptors (RARA, RARB a...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Gely-Pernot, Aurore, Raverdeau, Mathilde, Teletin, Marius, Vernet, Nadège, Féret, Betty, Klopfenstein, Muriel, Dennefeld, Christine, Davidson, Irwin, Benoit, Gérard, Mark, Manuel, Ghyselinck, Norbert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591280/
https://ncbi.nlm.nih.gov/pubmed/26427057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005501
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