Elevated nocturnal NEFA are an early signal for hyperinsulinaemic compensation during diet-induced insulin resistance in dogs

AIMS/HYPOTHESIS: A normal consequence of increased energy intake and insulin resistance is compensatory hyperinsulinaemia through increased insulin secretion and/or reduced insulin clearance. Failure of compensatory mechanisms plays a central role in the pathogenesis of type 2 diabetes mellitus; con...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Broussard, Josiane L., Kolka, Cathryn M., Castro, Ana V. B., Bediako, Isaac Asare, Paszkiewicz, Rebecca L., Szczepaniak, Edward W., Szczepaniak, Lidia S., Knutson, Kristen L., Kim, Stella P., Bergman, Richard N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591216/
https://ncbi.nlm.nih.gov/pubmed/26254577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3721-6
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