Insulin access to skeletal muscle is rapidly impaired during the early stages of diet-induced obesity

OBJECTIVE: Insulin must move from the blood to the interstitium to initiate signaling, yet access to the interstitium may be impaired in cases of insulin resistance, such as obesity. We investigated whether consuming a short- and long-term high-fat diet (HFD) impairs insulin access to skeletal muscl...

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Detalhes bibliográficos
Publicado no:Obesity (Silver Spring)
Main Authors: Broussard, Josiane L., Castro, Ana V.B., Iyer, Malini, Paszkiewicz, Rebecca L., Bediako, Isaac Asare, Szczepaniak, Lidia S., Szczepaniak, Edward W., Bergman, Richard N., Kolka, Cathryn M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004780/
https://ncbi.nlm.nih.gov/pubmed/27569119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21562
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