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p21(WAF1/CIP1) Expression is Differentially Regulated by Metformin and Rapamycin

The mammalian target of rapamycin (mTOR) pathway plays an important role in the development of diabetic nephropathy and other age-related diseases. One of the features of DN is the elevated expression of p21(WAF1/CIP1). However, the importance of the mTOR signalling pathway in p21 regulation is poor...

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Detalhes bibliográficos
Publicado no:Int J Chronic Dis
Main Authors: Molnar, Zoltan, Millward, Ann B., Tse, Wai, Demaine, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590942/
https://ncbi.nlm.nih.gov/pubmed/26464852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/327640
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