p21(WAF1/CIP1) Expression is Differentially Regulated by Metformin and Rapamycin

The mammalian target of rapamycin (mTOR) pathway plays an important role in the development of diabetic nephropathy and other age-related diseases. One of the features of DN is the elevated expression of p21(WAF1/CIP1). However, the importance of the mTOR signalling pathway in p21 regulation is poor...

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Bibliografiska uppgifter
I publikationen:Int J Chronic Dis
Huvudupphovsmän: Molnar, Zoltan, Millward, Ann B., Tse, Wai, Demaine, Andrew G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590942/
https://ncbi.nlm.nih.gov/pubmed/26464852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/327640
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