Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice

BACKGROUND: Coplanar polychlorinated biphenyls (PCBs) promote adipocyte inflammation and impair glucose homeostasis in lean mice. The diabetes-promoting effects of lipophilic PCBs have been observed only during weight loss in obese mice. The molecular mechanisms linking PCB exposures to impaired glu...

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Publicado en:Environ Health Perspect
Autores principales: Baker, Nicki A., Shoemaker, Robin, English, Victoria, Larian, Nika, Sunkara, Manjula, Morris, Andrew J., Walker, Mary, Yiannikouris, Frederique, Cassis, Lisa A.
Formato: Artigo
Lenguaje:Inglês
Publicado: NLM-Export 2015
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590748/
https://ncbi.nlm.nih.gov/pubmed/25734695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408594
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