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Preparation and evaluation of sustained-release solid dispersions co-loading gastrodin with borneol as an oral brain-targeting enhancer

Borneol is a traditional Chinese medicine that can promote drug absorption from the gastrointestinal tract and distribution to the brain. However, stomach irritation may occur when high doses of borneol are used. In the present work, gastrodin, the main bioactive ingredient of the traditional Chines...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Cai, Zheng, Lei, Xiaolu, Lin, Zhufen, Zhao, Jie, Wu, Feizhen, Yang, Zhaoxiang, Pu, Junxue, Liu, Zhongqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590720/
https://ncbi.nlm.nih.gov/pubmed/26579369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2013.12.012
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