Sustained release ivermectin-loaded solid lipid dispersion for subcutaneous delivery: in vitro and in vivo evaluation

This work aimed to develop a sustained release solid dispersion of ivermectin (IVM-SD) in a lipid matrix (hydrogenated castor oil, HCO) for subcutaneous delivery. Solvent-melting technology was employed to prepare IVM-SDs using HCO. The physicochemical properties of the IVM-SDs were evaluated by sca...

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Библиографические подробности
Опубликовано в: :Drug Deliv
Главные авторы: Lu, Mengmeng, Xiong, Dan, Sun, Weiwei, Yu, Tong, Hu, Zixia, Ding, Jiafeng, Cai, Yunpeng, Yang, Shizhuang, Pan, Baoliang
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240974/
https://ncbi.nlm.nih.gov/pubmed/28282989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1284945
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