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Preparation and evaluation of sustained-release solid dispersions co-loading gastrodin with borneol as an oral brain-targeting enhancer

Borneol is a traditional Chinese medicine that can promote drug absorption from the gastrointestinal tract and distribution to the brain. However, stomach irritation may occur when high doses of borneol are used. In the present work, gastrodin, the main bioactive ingredient of the traditional Chines...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharm Sin B
Hauptverfasser: Cai, Zheng, Lei, Xiaolu, Lin, Zhufen, Zhao, Jie, Wu, Feizhen, Yang, Zhaoxiang, Pu, Junxue, Liu, Zhongqiu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590720/
https://ncbi.nlm.nih.gov/pubmed/26579369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2013.12.012
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