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Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage

Autophagy and senescence have been described as central features of cell biology, but the interplay between these mechanisms remains obscure. Using a therapeutically relevant model of DNA damage-induced senescence in human glioma cells, we demonstrated that acute treatment with temozolomide induces...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Filippi-Chiela, Eduardo Cremonese, Silva, Mardja Manssur Bueno e, Thomé, Marcos Paulo, Lenz, Guido
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590630/
https://ncbi.nlm.nih.gov/pubmed/25701485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1009795
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