Free-cholesterol-mediated autophagy of ORMDL1 stimulates sphingomyelin biosynthesis

Cholesterol confers unique biophysical properties to the plasma membrane bilayer that are essential for maintaining optimal membrane fluidity, which in turn regulate multiple physiological functions required to promote cellular integrity and viability. Conversely, excessive cholesterol causes pathol...

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Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Wang, Shuhui, Robinet, Peggy, Smith, Jonathan D, Gulshan, Kailash
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Autophagic Punctum
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590593/
https://ncbi.nlm.nih.gov/pubmed/26042659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1052209
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