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ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading–induced autophagy
Eukaryotic cells have evolved robust mechanisms to counter excess cholesterol including redistribution of lipids into different compartments and compensatory up-regulation of phospholipid biosynthesis. We demonstrate here that excess cellular cholesterol increased the activity of the endoplasmic ret...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4378419/ https://ncbi.nlm.nih.gov/pubmed/25775599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422455112 |
| Oznake: |
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