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The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy

Melanoma is the most serious type of skin cancer and one of the most common cancers in the world. Advanced melanoma is often resistant to conventional therapies and has high potential for metastasis and low survival rates. Vemurafenib is a small molecule inhibitor of the BRAF serine-threonine kinase...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Wu, Chung-Pu, V. Ambudkar, Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590304/
https://ncbi.nlm.nih.gov/pubmed/26579371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2013.12.001
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