Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

Emerging evidence suggests pathological and immunoregulatory functions for IgG4 antibodies and IgG4(+) B cells in inflammatory diseases and malignancies. We previously reported that IgG4 antibodies restrict activation of immune effector cell functions and impair humoral responses in melanoma. Here,...

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Pubblicato in:Oncoimmunology
Autori principali: Karagiannis, Panagiotis, Villanova, Federica, Josephs, Debra H, Correa, Isabel, Van Hemelrijck, Mieke, Hobbs, Carl, Saul, Louise, Egbuniwe, Isioma U, Tosi, Isabella, Ilieva, Kristina M, Kent, Emma, Calonje, Eduardo, Harries, Mark, Fentiman, Ian, Taylor-Papadimitriou, Joyce, Burchell, Joy, Spicer, James F, Lacy, Katie E, Nestle, Frank O, Karagiannis, Sophia N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590000/
https://ncbi.nlm.nih.gov/pubmed/26451312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1032492
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