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Proteolytic processing of the neuronal ceroid lipofuscinosis related lysosomal protein CLN5

CLN5 is a soluble lysosomal glycoprotein. Deficiency in CLN5 protein causes neuronal ceroid lipofuscinosis, an inherited neurodegenerative lysosomal storage disorder. The function of CLN5 and how it affects lysosome activity are unclear. We identified two forms of the CLN5 protein present in most of...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: De Silva, Bhagya, Adams, Jessie, Lee, Stella Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589533/
https://ncbi.nlm.nih.gov/pubmed/26342652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.08.021
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