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Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice
Both CLN1 and CLN5 deficiencies lead to severe neurodegenerative diseases of childhood, known as neuronal ceroid lipofuscinoses (NCLs). The broadly similar phenotypes of NCL mouse models, and the potential for interactions between NCL proteins, raise the possibility of shared or convergent disease m...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597017/ https://ncbi.nlm.nih.gov/pubmed/23065637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010140 |
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