Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice

Both CLN1 and CLN5 deficiencies lead to severe neurodegenerative diseases of childhood, known as neuronal ceroid lipofuscinoses (NCLs). The broadly similar phenotypes of NCL mouse models, and the potential for interactions between NCL proteins, raise the possibility of shared or convergent disease m...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Blom, Tea, Schmiedt, Mia-Lisa, Wong, Andrew M., Kyttälä, Aija, Soronen, Jarkko, Jauhiainen, Matti, Tyynelä, Jaana, Cooper, Jonathan D., Jalanko, Anu
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Limited 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597017/
https://ncbi.nlm.nih.gov/pubmed/23065637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010140
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky