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Identification of Happyhour/MAP4K as alternative Hpo/Mst-like kinases in the Hippo kinase cascade

In Drosophila and mammals, the canonical Hippo kinase cascade is mediated by Hpo/Mst acting through the intermediary kinase Wts/Lats to phosphorylate the transcriptional coactivator Yki/YAP/TAZ. Despite recent reports linking Yki/YAP/TAZ activity to the actin cytoskeleton, the underlying mechanisms...

詳細記述

保存先:
書誌詳細
出版年:Dev Cell
主要な著者: Zheng, Yonggang, Wang, Wei, Liu, Bo, Deng, Hua, Uster, Eliza, Pan, Duojia
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589524/
https://ncbi.nlm.nih.gov/pubmed/26364751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.08.014
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