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NHERF-1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury

The intercellular adhesion molecule-1 (ICAM-1) is induced in mouse liver after bile duct ligation (BDL) and plays a key role in neutrophil-mediated liver injury in BDL mice. ICAM-1 has been shown to interact with the cytoskeletal ezrin-radixin-moesin (ERM) proteins that also interact with the PDZ pr...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Li, Man, Mennone, Albert, Soroka, Carol J., Hagey, Lee R., Ouyang, Xinshou, Weinman, Edward J., Boyer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589453/
https://ncbi.nlm.nih.gov/pubmed/26108984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27956
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