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Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver
The source of new hepatocytes in the uninjured liver has remained an open question. By lineage tracing using the Wnt-responsive gene Axin2, we identify a population of proliferating and self-renewing cells adjacent to the central vein in the liver lobule. These pericentral cells express the early li...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589224/ https://ncbi.nlm.nih.gov/pubmed/26245375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14863 |
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