Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas

To elucidate mechanisms underlying epidemiological findings of decreased risk of glioma development in patients with allergies and asthma, gliomas were induced in mice deficient for histidine decarboxylase (HDC), the enzyme responsible for histamine production. These mice exhibited shortened surviva...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncoimmunology
Prif Awduron: Ahn, Brian, Kohanbash, Gary, Ohkuri, Takayuki, Kosaka, Akemi, Chen, Xiaowei, Ikeura, Maki, Wang, Timothy C, Okada, Hideho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589044/
https://ncbi.nlm.nih.gov/pubmed/26451324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1047581
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