Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas

To elucidate mechanisms underlying epidemiological findings of decreased risk of glioma development in patients with allergies and asthma, gliomas were induced in mice deficient for histidine decarboxylase (HDC), the enzyme responsible for histamine production. These mice exhibited shortened surviva...

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Библиографические подробности
Опубликовано в: :Oncoimmunology
Главные авторы: Ahn, Brian, Kohanbash, Gary, Ohkuri, Takayuki, Kosaka, Akemi, Chen, Xiaowei, Ikeura, Maki, Wang, Timothy C, Okada, Hideho
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589044/
https://ncbi.nlm.nih.gov/pubmed/26451324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1047581
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