Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas

To elucidate mechanisms underlying epidemiological findings of decreased risk of glioma development in patients with allergies and asthma, gliomas were induced in mice deficient for histidine decarboxylase (HDC), the enzyme responsible for histamine production. These mice exhibited shortened surviva...

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Spremljeno u:
Bibliografski detalji
Izdano u:Oncoimmunology
Glavni autori: Ahn, Brian, Kohanbash, Gary, Ohkuri, Takayuki, Kosaka, Akemi, Chen, Xiaowei, Ikeura, Maki, Wang, Timothy C, Okada, Hideho
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589044/
https://ncbi.nlm.nih.gov/pubmed/26451324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1047581
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