Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas

To elucidate mechanisms underlying epidemiological findings of decreased risk of glioma development in patients with allergies and asthma, gliomas were induced in mice deficient for histidine decarboxylase (HDC), the enzyme responsible for histamine production. These mice exhibited shortened surviva...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Ahn, Brian, Kohanbash, Gary, Ohkuri, Takayuki, Kosaka, Akemi, Chen, Xiaowei, Ikeura, Maki, Wang, Timothy C, Okada, Hideho
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589044/
https://ncbi.nlm.nih.gov/pubmed/26451324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1047581
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