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Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation

Background: Epigenome-wide association scans (EWAS) are under way for many complex human traits, but EWAS power has not been fully assessed. We investigate power of EWAS to detect differential methylation using case-control and disease-discordant monozygotic (MZ) twin designs with genome-wide DNA me...

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Bibliografiska uppgifter
I publikationen:Int J Epidemiol
Huvudupphovsmän: Tsai, Pei-Chien, Bell, Jordana T
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588864/
https://ncbi.nlm.nih.gov/pubmed/25972603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv041
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