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Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation

Background: Epigenome-wide association scans (EWAS) are under way for many complex human traits, but EWAS power has not been fully assessed. We investigate power of EWAS to detect differential methylation using case-control and disease-discordant monozygotic (MZ) twin designs with genome-wide DNA me...

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Detalhes bibliográficos
Publicado no:Int J Epidemiol
Main Authors: Tsai, Pei-Chien, Bell, Jordana T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588864/
https://ncbi.nlm.nih.gov/pubmed/25972603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv041
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