Progesterone and the Repression of Myometrial Inflammation: The Roles of MKP-1 and the AP-1 System

Progesterone (P4) maintains uterine quiescence during pregnancy and its functional withdrawal is associated with increased prostaglandin synthesis and the onset of labor. In primary human myometrial cells, the glucocorticoid receptor (GR) rather than the P4 receptor mediates P4 antagonism of IL-1β-i...

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Bibliografiske detaljer
Udgivet i:Mol Endocrinol
Main Authors: Lei, K., Georgiou, E. X., Chen, L., Yulia, A., Sooranna, S. R., Brosens, J. J., Bennett, P. R., Johnson, M. R.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588734/
https://ncbi.nlm.nih.gov/pubmed/26280733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1122
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