Progesterone Acts via the Nuclear Glucocorticoid Receptor to Suppress IL-1β-Induced COX-2 Expression in Human Term Myometrial Cells

Progesterone is widely used to prolong gestation in women at risk of preterm labour (PTL), and acts at least in part via the inhibition of inflammatory cytokine-induced prostaglandin synthesis. This study investigates the mechanisms responsible for this inhibition in human myometrial cells. We used...

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Detalhes bibliográficos
Main Authors: Lei, Kaiyu, Chen, Li, Georgiou, Ektoras X., Sooranna, Suren R., Khanjani, Shirin, Brosens, Jan J., Bennett, Phillip R., Johnson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509141/
https://ncbi.nlm.nih.gov/pubmed/23209664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050167
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