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Progesterone and the Repression of Myometrial Inflammation: The Roles of MKP-1 and the AP-1 System

Progesterone (P4) maintains uterine quiescence during pregnancy and its functional withdrawal is associated with increased prostaglandin synthesis and the onset of labor. In primary human myometrial cells, the glucocorticoid receptor (GR) rather than the P4 receptor mediates P4 antagonism of IL-1β-i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Lei, K., Georgiou, E. X., Chen, L., Yulia, A., Sooranna, S. R., Brosens, J. J., Bennett, P. R., Johnson, M. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588734/
https://ncbi.nlm.nih.gov/pubmed/26280733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1122
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