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Practical approaches for evaluating adrenal toxicity in nonclinical safety assessment

The adrenal gland has characteristic morphological and biochemical features that render it particularly susceptible to the actions of xenobiotics. As is the case with other endocrine organs, the adrenal gland is under the control of upstream organs (hypothalamic-pituitary system) in vivo, often maki...

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Detalhes bibliográficos
Publicado no:J Toxicol Pathol
Main Authors: Inomata, Akira, Sasano, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588206/
https://ncbi.nlm.nih.gov/pubmed/26441474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2015-0025
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