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Antibody Drug Conjugates: Nonclinical Safety Considerations

Antibody drug conjugates (ADCs) are biopharmaceutical molecules consisting of a cytotoxic small molecule covalently linked to a targeted protein carrier via a stable cleavable or noncleavable linker. The process of conjugation yields a highly complex molecule with biochemical properties that are dis...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:AAPS J
Päätekijät: Hinrichs, Mary Jane Masson, Dixit, Rakesh
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540738/
https://ncbi.nlm.nih.gov/pubmed/26024656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9790-0
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