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Safety and Tolerability of Antibody-Drug Conjugates in Cancer
Antibody-drug conjugates are monoclonal antibodies attached to biologically active drugs through chemical linkers that deliver and release cytotoxic agents at the tumor site, reducing the likelihood of systemic exposure and therefore toxicity. Currently, there are about 110 ongoing studies implement...
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| Veröffentlicht in: | Drug Saf |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399172/ https://ncbi.nlm.nih.gov/pubmed/30649747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-018-0775-7 |
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