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Antibody Drug Conjugates: Nonclinical Safety Considerations
Antibody drug conjugates (ADCs) are biopharmaceutical molecules consisting of a cytotoxic small molecule covalently linked to a targeted protein carrier via a stable cleavable or noncleavable linker. The process of conjugation yields a highly complex molecule with biochemical properties that are dis...
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| Publicado en: | AAPS J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer US
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540738/ https://ncbi.nlm.nih.gov/pubmed/26024656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9790-0 |
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