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Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying

In this study, two types of biodegradable polycation (PAsp(DET) homopolymer and PEG-PAsp(DET) copolymer) were applied as vectors for inhalable dry gene powders prepared by spray freeze drying (SFD). The prepared dry gene powders had spherical and porous structures with a 5~10-μm diameter, and the in...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Okuda, Tomoyuki, Suzuki, Yumiko, Kobayashi, Yuko, Ishii, Takehiko, Uchida, Satoshi, Itaka, Keiji, Kataoka, Kazunori, Okamoto, Hirokazu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588198/
https://ncbi.nlm.nih.gov/pubmed/26343708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics7030233
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