Investigating heart-specific toxicity of amyloidogenic immunoglobulin light chains: A lesson from C. elegans

Abnormalities in protein folding are involved in many localized and systemic diseases, all of which are characterized by insoluble amyloid formation and deposition. In immunoglobulin light chain (LC) amyloidosis, the most frequent systemic form of amyloidosis, the amyloid involvement of the heart di...

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Detalhes bibliográficos
Publicado no:Worm
Main Authors: Diomede, Luisa, Rognoni, Paola, Lavatelli, Francesca, Romeo, Margherita, di Fonzo, Andrea, Foray, Claudia, Fiordaliso, Fabio, Palladini, Giovanni, Valentini, Veronica, Perfetti, Vittorio, Salmona, Mario, Merlini, Giampaolo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Commentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588172/
https://ncbi.nlm.nih.gov/pubmed/26430549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624046.2014.965590
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