Investigating heart-specific toxicity of amyloidogenic immunoglobulin light chains: A lesson from C. elegans

Abnormalities in protein folding are involved in many localized and systemic diseases, all of which are characterized by insoluble amyloid formation and deposition. In immunoglobulin light chain (LC) amyloidosis, the most frequent systemic form of amyloidosis, the amyloid involvement of the heart di...

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Published in:Worm
Main Authors: Diomede, Luisa, Rognoni, Paola, Lavatelli, Francesca, Romeo, Margherita, di Fonzo, Andrea, Foray, Claudia, Fiordaliso, Fabio, Palladini, Giovanni, Valentini, Veronica, Perfetti, Vittorio, Salmona, Mario, Merlini, Giampaolo
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588172/
https://ncbi.nlm.nih.gov/pubmed/26430549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624046.2014.965590
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