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Spatial Moran Models I. Stochastic Tunneling in the Neutral Case

We consider a multistage cancer model in which cells are arranged in a d-dimensional integer lattice. Starting with all wild-type cells, we prove results about the distribution of the first time when two neutral mutations have accumulated in some cell in dimensions d ≥ 2, extending work done by Koma...

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Pubblicato in:Ann Appl Probab
Autori principali: Durrett, Richard, Moseley, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587779/
https://ncbi.nlm.nih.gov/pubmed/26430352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/13-AAP989
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