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Spatial Moran Models I. Stochastic Tunneling in the Neutral Case
We consider a multistage cancer model in which cells are arranged in a d-dimensional integer lattice. Starting with all wild-type cells, we prove results about the distribution of the first time when two neutral mutations have accumulated in some cell in dimensions d ≥ 2, extending work done by Koma...
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| Udgivet i: | Ann Appl Probab |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587779/ https://ncbi.nlm.nih.gov/pubmed/26430352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/13-AAP989 |
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