Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney

Epigenetic mechanisms may underlie the progression of diabetic kidney disease. Because the kidney is a heterogeneous organ with different cell types, we investigated DNA methylation status of the kidney in a cell type–specific manner. We first identified genes specifically demethylated in the normal...

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Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Marumo, Takeshi, Yagi, Shintaro, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Watanabe, Atsushi, Ueda, Kohei, Hirahashi, Junichi, Hishikawa, Keiichi, Sakurai, Hiroyuki, Shiota, Kunio, Fujita, Toshiro
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2015
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587689/
https://ncbi.nlm.nih.gov/pubmed/25653098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014070665
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