Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension

Maternal malnutrition, which causes prenatal exposure to excessive glucocorticoid, induces adverse metabolic programming, leading to hypertension in offspring. In offspring of pregnant rats receiving a low-protein diet or dexamethasone, a synthetic glucocorticoid, mRNA expression of angiotensin rece...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kawakami-Mori, Fumiko, Nishimoto, Mitsuhiro, Reheman, Latapati, Kawarazaki, Wakako, Ayuzawa, Nobuhiro, Ueda, Kohei, Hirohama, Daigoro, Kohno, Daisuke, Oba, Shigeyoshi, Shimosawa, Tatsuo, Marumo, Takeshi, Fujita, Toshiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238751/
https://ncbi.nlm.nih.gov/pubmed/30385711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95625
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