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PGI(2) Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation

Renal inflammation is known to be involved in salt-induced renal damage, leading to end-stage renal disease. This study aims to evaluate the role of inflammation in anti-inflammatory and renoprotective effects of beraprost sodium (BPS), a prostaglandin I(2) (PGI(2)) analog, in Dahl salt-sensitive (D...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Hirohama, Daigoro, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Marumo, Takeshi, Shibata, Shigeru, Fujita, Toshiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353033/
https://ncbi.nlm.nih.gov/pubmed/32580367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124433
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