Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependent

Animal models demonstrate that exposure to supraphysiological oxygen during the neonatal period compromises both lung and pulmonary vascular development, resulting in a phenotype comparable to bronchopulmonary dysplasia (BPD). Our prior work in murine models identified postnatal maturation of antiox...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Datta, Ankur, Kim, Gina A., Taylor, Joann M., Gugino, Sylvia F., Farrow, Kathryn N., Schumacker, Paul T., Berkelhamer, Sara K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587628/
https://ncbi.nlm.nih.gov/pubmed/26092998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00176.2014
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