Right ventricular cyclic nucleotide signaling is decreased in hyperoxia-induced pulmonary hypertension in neonatal mice

Pulmonary hypertension (PH) and right ventricular hypertrophy (RVH) affect 25–35% of premature infants with significant bronchopulmonary dysplasia (BPD), increasing morbidity and mortality. We sought to determine the role of phosphodiesterase 5 (PDE5) in the right ventricle (RV) and left ventricle (...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Heilman, Rachel P., Lagoski, Megan B., Lee, Keng Jin, Taylor, Joann M., Kim, Gina A., Berkelhamer, Sara K., Steinhorn, Robin H., Farrow, Kathryn N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469878/
https://ncbi.nlm.nih.gov/pubmed/25862831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00569.2014
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