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Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependent

Animal models demonstrate that exposure to supraphysiological oxygen during the neonatal period compromises both lung and pulmonary vascular development, resulting in a phenotype comparable to bronchopulmonary dysplasia (BPD). Our prior work in murine models identified postnatal maturation of antiox...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Datta, Ankur, Kim, Gina A., Taylor, Joann M., Gugino, Sylvia F., Farrow, Kathryn N., Schumacker, Paul T., Berkelhamer, Sara K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587628/
https://ncbi.nlm.nih.gov/pubmed/26092998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00176.2014
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