Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

To explore the potential of tumor-specific DNA as a biomarker for head and neck squamous cell carcinomas (HNSCC), we queried DNA from saliva or plasma of 93 HNSCC patients. We searched for somatic mutations or human papillomavirus genes, collectively referred to as tumor DNA. When both plasma and sa...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Transl Med
Κύριοι συγγραφείς: Wang, Yuxuan, Springer, Simeon, Mulvey, Carolyn L., Silliman, Natalie, Schaefer, Joy, Sausen, Mark, James, Nathan, Rettig, Eleni M., Guo, Theresa, Pickering, Curtis R., Bishop, Justin A., Chung, Christine H., Califano, Joseph A., Eisele, David W., Fakhry, Carole, Gourin, Christine G., Ha, Patrick K., Kang, Hyunseok, Kiess, Ana, Koch, Wayne M., Myers, Jeffrey N., Quon, Harry, Richmon, Jeremy D., Sidransky, David, Tufano, Ralph P., Westra, William H., Bettegowda, Chetan, Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Agrawal, Nishant
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587492/
https://ncbi.nlm.nih.gov/pubmed/26109104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa8507
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